Gene:  NEB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes nebulin a giant protein component of the cytoskeletal matrix that coexists with the thick and thin filaments within the sarcomeres of skeletal muscle. In most vertebrates nebulin accounts for 3 to 4% of the total myofibrillar protein. The encoded protein contains approximately 30-amino acid long modules that can be classified into 7 types and other repeated modules. Protein isoform sizes vary from 600 to 800 kD due to alternative splicing that is tissue- species-and developmental stage-specific. Of the 183 exons in the nebulin gene at least 43 are alternatively spliced although exons 143 and 144 are not found in the same transcript. Of the several thousand transcript variants predicted for nebulin the RefSeq Project has decided to create three representative RefSeq records. Mutations in this gene are associated with recessive nemaline myopathy. [provided by RefSeq Sep 2009]

PrimePCR™ SYBR® Green Assay: NEB, Human
nebulin

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011772
Info:   Same primer pair as used in probe assay qHsaCIP0028175
List Price:    $142.00
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PrimePCR™ Probe Assay: NEB, Human
nebulin

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028175
List Price:    $208.00
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