Gene:  MVK, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate and mevalonate kinase a key early enzyme in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria a disease characterized psychomotor retardation failure to thrive hepatosplenomegaly anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome a disorder characterized by recurrent episodes of fever associated with lymphadenopathy arthralgia gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: MVK, Human
mevalonate kinase

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0022200
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: MVK, Human
mevalonate kinase

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043340
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0050602
List Price:    $142.00
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PrimePCR™ Probe Assay: MVK, Human
mevalonate kinase

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050602
List Price:    $208.00
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    Related pathways not available
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