Gene:  MRVI1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein which is found in the membrane of the endoplasmic reticulum is similar to Jaw1 a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release. Studies in mouse suggest that MRV integration at Mrvi1 induces myeloid leukemia by altering the expression of a gene important for myeloid cell growth and/or differentiation and thus this gene may function as a myeloid leukemia tumor suppressor gene. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene and alternative translation start sites including a non-AUG (CUG) start site are used. [provided by RefSeq May 2011]

PrimePCR™ SYBR® Green Assay: MRVI1, Human
murine retrovirus integration site 1 homolog

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042329
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0049592
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: MRVI1, Human
murine retrovirus integration site 1 homolog

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010432
List Price:    $146.00
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PrimePCR™ Probe Assay: MRVI1, Human
murine retrovirus integration site 1 homolog

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049592
List Price:    $214.00
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