Gene:  MEP1B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted whereas oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability renal gene expression profiles and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq Oct 2011]

PrimePCR™ SYBR® Green Assay: MEP1B, Human
meprin A, beta

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0015287
Info:   Same primer pair as used in probe assay qHsaCIP0029834
List Price:    $142.00
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PrimePCR™ Probe Assay: MEP1B, Human
meprin A, beta

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029834
List Price:    $208.00
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