Gene:  MED12, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene mediator complex subunit 12 (MED12) along with MED13 CDK8 kinase and cyclin C. The CDK8 subcomplex modulates Mediator-polymerase II interactions and thereby regulates transcription initiation and reinitation rates. The MED12 protein is essential for activating CDK8 kinase. Defects in this gene cause X-linked Opitz-Kaveggia syndrome also known as FG syndrome and Lujan-Fryns syndrome. [provided by RefSeq Aug 2009]

PrimePCR™ SYBR® Green Assay: MED12, Human
mediator complex subunit 12

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001926
Info:   Same primer pair as used in probe assay qHsaCEP0024217
List Price:    $174.00
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PrimePCR™ Probe Assay: MED12, Human
mediator complex subunit 12

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024217
List Price:    $255.00
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