Gene:  MAPK8IP1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1 a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq May 2011]

PrimePCR™ SYBR® Green Assay: MAPK8IP1, Human
mitogen-activated protein kinase 8 interacting protein 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0004039
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: MAPK8IP1, Human
mitogen-activated protein kinase 8 interacting protein 1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043912
Info:   Same primer pair as used in probe assay qHsaCEP0051174
List Price:    $142.00
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PrimePCR™ Probe Assay: MAPK8IP1, Human
mitogen-activated protein kinase 8 interacting protein 1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051174
List Price:    $208.00
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    Related pathways not available
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