Gene:  MAP4K4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1 MAP2K4/MKK4 and MAP2K7/MKK7 which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: MAP4K4, Human
mitogen-activated protein kinase kinase kinase kinase 4

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009017
Info:   Same primer pair as used in probe assay qHsaCIP0027019
List Price:    $142.00
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PrimePCR™ Probe Assay: MAP4K4, Human
mitogen-activated protein kinase kinase kinase kinase 4

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0027019
List Price:    $208.00
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