Gene:  KCNQ4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2) an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: KCNQ4, Human
potassium voltage-gated channel, KQT-like subfamily, member 4

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043717
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0050979
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: KCNQ4, Human
potassium voltage-gated channel, KQT-like subfamily, member 4

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009454
List Price:    $146.00
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PrimePCR™ Probe Assay: KCNQ4, Human
potassium voltage-gated channel, KQT-like subfamily, member 4

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050979
List Price:    $214.00
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