Gene:  KCNA1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6) and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: KCNA1, Human
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0021102
Info:   Same primer pair as used in probe assay qHsaCEP0032913
List Price:    $142.00
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PrimePCR™ Probe Assay: KCNA1, Human
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0032913
List Price:    $208.00
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