Gene:  INHBA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore the beta A subunit forms a homodimer activin A and also joins with a beta B subunit to form a heterodimer activin AB both of which stimulate FSH secretion. Finally it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: INHBA, Human
inhibin, beta A

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010613
Info:   Same primer pair as used in probe assay qHsaCIP0027657
List Price:    $142.00
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