Gene:  IL6ST, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a signal transducer shared by many cytokines including interleukin 6 (IL6) ciliary neurotrophic factor (CNTF) leukemia inhibitory factor (LIF) and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6 a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq Jul 2010]

PrimePCR™ SYBR® Green Assay: IL6ST, Human
interleukin 6 signal transducer (gp130, oncostatin M receptor)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0007540
Info:   Same primer pair as used in probe assay qHsaCIP0026506
List Price:    $142.00
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PrimePCR™ Probe Assay: IL6ST, Human
interleukin 6 signal transducer (gp130, oncostatin M receptor)

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026506
List Price:    $208.00
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