Gene:  HSD11B1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition the encoded protein can catalyze the reverse reaction the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq May 2011]

PrimePCR™ SYBR® Green Assay: HSD11B1, Human
hydroxysteroid (11-beta) dehydrogenase 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0016997
Info:   Same primer pair as used in probe assay qHsaCIP0030952
List Price:    $142.00
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PrimePCR™ Probe Assay: HSD11B1, Human
hydroxysteroid (11-beta) dehydrogenase 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030952
List Price:    $208.00
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    Related pathways not available
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