Gene:  HLA-DMA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB) both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide exons 2 and 3 encode the two extracellular domains exon 4 encodes the transmembrane domain and the cytoplasmic tail. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: HLA-DMA, Human
major histocompatibility complex, class II, DM alpha

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0037293
Info:   Same primer pair as used in probe assay qHsaCEP0040016
List Price:    $142.00
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PrimePCR™ Probe Assay: HLA-DMA, Human
major histocompatibility complex, class II, DM alpha

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0040016
List Price:    $208.00
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