Gene:  GRM7, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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L-glutamate is the major excitatory neurotransmitter in the central nervous system and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology putative signal transduction mechanisms and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4 GRM6 GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jun 2009]

PrimePCR™ SYBR® Green Assay: GRM7, Human
glutamate receptor, metabotropic 7

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0004157
Info:   Recommended - best coverage
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: GRM7, Human
glutamate receptor, metabotropic 7

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0048059
Info:   Same primer pair as used in probe assay qHsaCEP0055319
List Price:    $146.00
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PrimePCR™ Probe Assay: GRM7, Human
glutamate receptor, metabotropic 7

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055319
List Price:    $214.00
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