Gene:  GRM6, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology putative signal transduction mechanisms and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4 GRM6 GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq Feb 2012]

PrimePCR™ SYBR® Green Assay: GRM6, Human
glutamate receptor, metabotropic 6

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0033963
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: GRM6, Human
glutamate receptor, metabotropic 6

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043480
Info:   Same primer pair as used in probe assay qHsaCEP0050742
List Price:    $146.00
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PrimePCR™ Probe Assay: GRM6, Human
glutamate receptor, metabotropic 6

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050742
List Price:    $214.00
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