Gene:  GNB3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Heterotrimeric guanine nucleotide-binding proteins (G proteins) which integrate signals between receptors and effector proteins are composed of an alpha a beta and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional splice variants may exist for this gene but they have not been fully described. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: GNB3, Human
guanine nucleotide binding protein (G protein), beta polypeptide 3

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013618
Info:   Same primer pair as used in probe assay qHsaCIP0028951
List Price:    $142.00
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PrimePCR™ Probe Assay: GNB3, Human
guanine nucleotide binding protein (G protein), beta polypeptide 3

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028951
List Price:    $208.00
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