Gene:  GABRA4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4 which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq Feb 2011]

PrimePCR™ SYBR® Green Assay: GABRA4, Human
gamma-aminobutyric acid (GABA) A receptor, alpha 4

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036408
Info:   Same primer pair as used in probe assay qHsaCEP0039132
List Price:    $142.00
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PrimePCR™ Probe Assay: GABRA4, Human
gamma-aminobutyric acid (GABA) A receptor, alpha 4

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039132
List Price:    $208.00
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