Gene:  FGFR3, Human

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This gene encodes a member of the fibroblast growth factor receptor (FGFR) family with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq Jul 2009]

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PrimePCR™ SYBR® Green Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0004573
List Price:    $138.00
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PrimePCR™ SYBR® Green Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042267
Info:   Same primer pair as used in probe assay qHsaCEP0049530
List Price:    $138.00
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Add to Custom Plate
PrimePCR™ Probe Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049530
List Price:    $202.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5002765
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0004573; Exonic
List Price:    $138.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5007214
Info:   EG; Same primer pair as used in qPCR assay qHsaCED0042267; exonic
List Price:    $138.00
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PrimePCR™ ddPCR™ Copy Number Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP1000503
Info:   FAM; 69nt amplicon; crosses exon-intron junction; FAM version of FGFR3 (dHsaCP2506340)
 
Fluorophore:   FAM
List Price:    $254.00
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 p.Y373C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000103
Info:   75nt amplicon; exonic
List Price:    $254.00
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 WT for p.Y373C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2000104
Info:   75nt amplicon; exonic
List Price:    $207.00
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 p.G380R, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2500516
Info:   60nt amplicon; exonic
List Price:    $207.00
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 WT for p.G380R, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2500517
Info:   60nt amplicon; exonic
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PrimePCR™ ddPCR™ Copy Number Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Copy Number Variation
Unique Assay ID: dHsaCP2506340
Info:   HEX; 69nt amplicon; crosses exon-intron junction; HEX version of FGFR3 (dHsaCP1000503)
 
Fluorophore:   HEX
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 p.G370C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506742
Info:   56nt amplicon; exonic
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 WT for p.G370C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506743
Info:   56nt amplicon; exonic
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 p.S249C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506760
Info:   57nt amplicon; crosses exon-intron junction
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 WT for p.S249C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506761
Info:   57nt amplicon; crosses exon-intron junction
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 p.S371C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506802
Info:   75nt amplicon; exonic
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 WT for p.S371C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506803
Info:   75nt amplicon; exonic
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 p.R248C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506906
Info:   57nt amplicon; crosses exon-intron junction
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PrimePCR™ ddPCR™ Mutation Assay: FGFR3 WT for p.R248C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection
Unique Assay ID: dHsaCP2506907
Info:   57nt amplicon; crosses exon-intron junction
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PrimePCR™ ddPCR™ Expression Probe Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5032740
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049530; exonic
 
Fluorophore:   FAM
List Price:    Inquire
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PrimePCR™ ddPCR™ Expression Probe Assay: FGFR3, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5032741
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0049530; exonic
 
Fluorophore:   HEX
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.F384L, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2500970
Info:   69nt amplicon; exonic; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.F384L, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2500971
Info:   69nt amplicon; exonic; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.K650M, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501098
Info:   65nt amplicon; crosses exon-intron junction; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.K650M, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501099
Info:   65nt amplicon; crosses exon-intron junction; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.A369A, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501646
Info:   70nt amplicon; crosses exon-intron junction; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.A369A, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501647
Info:   70nt amplicon; crosses exon-intron junction; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.G370C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501668
Info:   70nt amplicon; crosses exon-intron junction; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.G370C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2501669
Info:   70nt amplicon; crosses exon-intron junction; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.K650Q, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2503334
Info:   55nt amplicon; crosses exon-intron junction; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.K650Q, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2503335
Info:   55nt amplicon; crosses exon-intron junction; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.K650E, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2503634
Info:   55nt amplicon; crosses exon-intron junction; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.K650E, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2503635
Info:   55nt amplicon; crosses exon-intron junction; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.K650T, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504118
Info:   65nt amplicon; crosses exon-intron junction; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.K650T, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504119
Info:   65nt amplicon; crosses exon-intron junction; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.A391E, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504736
Info:   57nt amplicon; exonic; in silico
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.A391E, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2504737
Info:   57nt amplicon; exonic; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.S371C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2505258
Info:   75nt amplicon; exonic; in silico
List Price:    Inquire
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PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.S371C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2505259
Info:   75nt amplicon; exonic; in silico
List Price:    Inquire
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Quantity:  
 
PrimePCR™ ddPCR™ Mutation Assay:FGFR3 p.Y373C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2506942
Info:   75nt amplicon; exonic; in silico
List Price:    Inquire
Your Price:   Inquire
Quantity:  
 
PrimePCR™ ddPCR™ Mutation Assay:FGFR3 WT for p.Y373C, Human
fibroblast growth factor receptor 3

Assay Type: Probe
Application: Mutation Detection in silico design
Unique Assay ID: dHsaIS2506943
Info:   75nt amplicon; exonic; in silico
List Price:    Inquire
Your Price:   Inquire
Quantity:  
 
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