Gene:  FGFR2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the fibroblast growth factor receptor family where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region composed of three immunoglobulin-like domains a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors setting in motion a cascade of downstream signals ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic basic and/or keratinocyte growth factor depending on the isoform. Mutations in this gene are associated with Crouzon syndrome Pfeiffer syndrome Craniosynostosis Apert syndrome Jackson-Weiss syndrome Beare-Stevenson cutis gyrata syndrome Saethre-Chotzen syndrome and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq Jan 2009]

PrimePCR™ SYBR® Green Assay: FGFR2, Human
fibroblast growth factor receptor 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0021928
Info:   Same primer pair as used in probe assay qHsaCIP0033242
List Price:    $142.00
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PrimePCR™ Probe Assay: FGFR2, Human
fibroblast growth factor receptor 2

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0033242
List Price:    $208.00
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