Gene:  FBLN5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a secreted extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However its expression is reinduced in balloon-injured vessels and atherosclerotic lesions notably in intimal vascular smooth muscle cells and endothelial cells. Therefore the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa autosomal recessive cutis laxa type I (CL type I) and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: FBLN5, Human
fibulin 5

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044948
Info:   Same primer pair as used in probe assay qHsaCEP0052210
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PrimePCR™ SYBR® Green Assay: FBLN5, Human
fibulin 5

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0011098
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PrimePCR™ Probe Assay: FBLN5, Human
fibulin 5

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052210
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    Related pathways not available
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