Gene:  FADD, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain this protein can be recruited by TNFRSF6/Fas-receptor tumor necrosis factor receptor TNFRSF25 and TNFSF10/TRAIL-receptor and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein which allows it to recruit caspase-8 and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: FADD, Human
Fas (TNFRSF6)-associated via death domain

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0019883
Info:   Recommended - best efficiency
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: FADD, Human
Fas (TNFRSF6)-associated via death domain

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046520
Info:   Same primer pair as used in probe assay qHsaCEP0053781
List Price:    $142.00
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PrimePCR™ Probe Assay: FADD, Human
Fas (TNFRSF6)-associated via death domain

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053781
List Price:    $208.00
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