Gene:  F11, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome a blood coagulation abnormality. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: F11, Rat
Coagulation factor XI

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCED0008227
List Price:    $146.00
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PrimePCR™ Probe Assay: F11, Rat
Coagulation factor XI

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qRnoCEP0030058
List Price:    $214.00
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