Gene:  ERCC5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes including RNA polymerase II transcription and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G) which is also referred to as xeroderma pigmentosum VII (XP7) a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome which is characterized by severe growth defects mental retardation and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic immunoglobulin-like variable motif containing) gene. [provided by RefSeq Feb 2011]

PrimePCR™ SYBR® Green Assay: ERCC5, Human
excision repair cross-complementing rodent repair deficiency, complementation group 5

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0044577
Info:   Same primer pair as used in probe assay qHsaCEP0051839
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: ERCC5, Human
excision repair cross-complementing rodent repair deficiency, complementation group 5

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0018588
Info:   Recommended - best coverage
List Price:    $146.00
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PrimePCR™ Probe Assay: ERCC5, Human
excision repair cross-complementing rodent repair deficiency, complementation group 5

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0051839
List Price:    $214.00
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