Gene:  ERBB2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

Why PrimePCR?

PrimePCR
Lookup Tool
Design and Validation of Real-Time PCR Primers-test
Pathway Curation
and Array Design Strategy
Control and Reference Assays for Real-Time PCR

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported with the most common allele Ile654/Ile655 shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers including breast and ovarian tumors. Alternative splicing results in several additional transcript variants some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ERBB2, Human
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045039
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0052301
List Price:    $142.00
Your Price:   Log In
Quantity:  
 
Add to Custom Plate
PrimePCR™ SYBR® Green Assay: ERBB2, Human
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012766
List Price:    $142.00
Your Price:   Log In
Quantity:  
 
Add to Custom Plate
PrimePCR™ Probe Assay: ERBB2, Human
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0052301
List Price:    $208.00
Your Price:   Log In
Quantity:  
 
Number Description Download