Gene:  EIF4G1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants some of which are derived from alternative promoter usage. [provided by RefSeq Aug 2010]

PrimePCR™ SYBR® Green Assay: EIF4G1, Human
eukaryotic translation initiation factor 4 gamma, 1

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0002665
Info:   Same primer pair as used in probe assay qHsaCEP0024464
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PrimePCR™ Probe Assay: EIF4G1, Human
eukaryotic translation initiation factor 4 gamma, 1

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0024464
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