Gene:  DUSP8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK SAPK/JNK p38) which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases different tissue distribution and subcellular localization and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38 is expressed predominantly in the adult brain heart and skeletal muscle is localized in the cytoplasm and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: DUSP8, Human
dual specificity phosphatase 8

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0034290
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: DUSP8, Human
dual specificity phosphatase 8

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047680
Info:   Same primer pair as used in probe assay qHsaCEP0054940
List Price:    $142.00
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PrimePCR™ Probe Assay: DUSP8, Human
dual specificity phosphatase 8

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0054940
List Price:    $208.00
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