Gene:  DCC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq Oct 2009]

PrimePCR™ SYBR® Green Assay: DCC, Human
deleted in colorectal carcinoma

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0047904
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0055164
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: DCC, Human
deleted in colorectal carcinoma

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0015678
List Price:    $142.00
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PrimePCR™ Probe Assay: DCC, Human
deleted in colorectal carcinoma

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0055164
List Price:    $208.00
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    Related pathways not available
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