Gene:  CTNNB1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally this protein binds to the product of the APC gene which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC) pilomatrixoma (PTR) medulloblastoma (MDB) and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq Oct 2009]

PrimePCR™ SYBR® Green Assay: CTNNB1, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046518
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0053779
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: CTNNB1, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0010363
List Price:    $142.00
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PrimePCR™ Probe Assay: CTNNB1, Human
catenin (cadherin-associated protein), beta 1, 88kDa

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053779
List Price:    $208.00
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