Gene:  CST3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily including the type 1 cystatins (stefins) type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions establishing its role in vascular disease. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CST3, Human
cystatin C

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042870
Info:   Same primer pair as used in probe assay qHsaCEP0050132
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: CST3, Human
cystatin C

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012666
Info:   Recommended - best coverage
List Price:    $142.00
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PrimePCR™ Probe Assay: CST3, Human
cystatin C

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050132
List Price:    $208.00
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