Gene:  COMT, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines including the neurotransmitters dopamine epinephrine and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances COMT is important in the metabolism of catechol drugs used in the treatment of hypertension asthma and Parkinson disease. COMT is found in two forms in tissues a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq Sep 2008]

PrimePCR™ SYBR® Green Assay: COMT, Human
catechol-O-methyltransferase

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0001845
Info:   Recommended - best coverage
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: COMT, Human
catechol-O-methyltransferase

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0042669
Info:   Same primer pair as used in probe assay qHsaCEP0049931
List Price:    $142.00
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PrimePCR™ Probe Assay: COMT, Human
catechol-O-methyltransferase

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0049931
List Price:    $208.00
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