Gene:  COCH, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is highly conserved in human mouse and chicken showing 94% and 79% amino acid identity of human to mouse and chicken sequences respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits consistent with mucopolysaccharide ground substance in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq Oct 2008]

PrimePCR™ SYBR® Green Assay: COCH, Human
coagulation factor C homolog, cochlin (Limulus polyphemus)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036367
Info:   Same primer pair as used in probe assay qHsaCEP0039091
List Price:    $146.00
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PrimePCR™ Probe Assay: COCH, Human
coagulation factor C homolog, cochlin (Limulus polyphemus)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039091
List Price:    $214.00
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