Gene:  Cldn5, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a critical component of endothelial tight junctions that control pericellular permeability. The knockout mice lacking this gene died within 10 h of birth and the blood-brain barrier in these mice against small molecules was selectively affected. This gene is expressed strongly in endothelium of normal lung and plays a regulation role during acrolein-induced acute lung injury. [provided by RefSeq Aug 2010]

PrimePCR™ SYBR® Green Assay: Cldn5, Mouse
Claudin 5

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qMmuCED0001017
Info:   Same primer pair as used in probe assay qMmuCEP0031923
List Price:    $142.00
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PrimePCR™ Probe Assay: Cldn5, Mouse
Claudin 5

Assay Type: Probe
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qMmuCEP0031923
List Price:    $208.00
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