Gene:  CLCF1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene is a member of the glycoprotein (gp)130 cytokine family and encodes cardiotrophin-like cytokine factor 1 (CLCF1). CLCF1 forms a heterodimer complex with cytokine receptor-like factor 1 (CRLF1). This dimer competes with ciliary neurotrophic factor (CNTF) for binding to the ciliary neurotrophic factor receptor (CNTFR) complex and activates the Jak-STAT signaling cascade. CLCF1 can be actively secreted from cells by forming a complex with soluble type I CRLF1 or soluble CNTFR. CLCF1 is a potent neurotrophic factor B-cell stimulatory agent and neuroendocrine modulator of pituitary corticotroph function. Defects in CLCF1 cause cold-induced sweating syndrome 2 (CISS2). This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq Oct 2009]

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PrimePCR™ SYBR® Green Assay: CLCF1, Human
cardiotrophin-like cytokine factor 1

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0014242
Info:   Same primer pair as used in probe assay qHsaCIP0029279
List Price:    $142.00
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PrimePCR™ Probe Assay: CLCF1, Human
cardiotrophin-like cytokine factor 1

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0029279
List Price:    $208.00
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PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CLCF1, Human
cardiotrophin-like cytokine factor 1

Assay Type: EvaGreen
Application: Gene Expression
Unique Assay ID: dHsaEG5019929
Info:   EG; Same primer pair as used in qPCR assay qHsaCID0014242; Intron-spanning
List Price:    $142.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CLCF1, Human
cardiotrophin-like cytokine factor 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5052078
Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0029279; Intron-spanning
 
Fluorophore:   FAM
List Price:    $213.00
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PrimePCR™ ddPCR™ Expression Probe Assay: CLCF1, Human
cardiotrophin-like cytokine factor 1

Assay Type: Probe
Application: Gene Expression
Unique Assay ID: dHsaCPE5052079
Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0029279; Intron-spanning
 
Fluorophore:   HEX
List Price:    $213.00
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