Gene:  CHRNA4, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a nicotinic acetylcholine receptor which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq Feb 2012]

PrimePCR™ SYBR® Green Assay: CHRNA4, Human
cholinergic receptor, nicotinic, alpha 4

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006845
Info:   Same primer pair as used in probe assay qHsaCIP0026313
List Price:    $146.00
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PrimePCR™ Probe Assay: CHRNA4, Human
cholinergic receptor, nicotinic, alpha 4

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026313
List Price:    $214.00
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