Gene:  CEP57, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization and the C-terminal half is required for nucleating bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2) sorting nexin 6 Ran-binding protein M and the kinesins KIF3A and KIF3B and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome a rare autosomal recessive disorder. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

PrimePCR™ SYBR® Green Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0046347
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0053608
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0009243
List Price:    $142.00
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PrimePCR™ Probe Assay: CEP57, Human
centrosomal protein 57kDa

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053608
List Price:    $208.00
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