Gene:  CASP14, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits large and small that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation which is important for the formation of the skin barrier. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CASP14, Human
caspase 14, apoptosis-related cysteine peptidase

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0017034
Info:   Same primer pair as used in probe assay qHsaCIP0030975
List Price:    $142.00
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PrimePCR™ Probe Assay: CASP14, Human
caspase 14, apoptosis-related cysteine peptidase

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030975
List Price:    $208.00
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