Gene:  CARD8, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation CASP1-dependent IL1B secretion and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq May 2010]

PrimePCR™ SYBR® Green Assay: CARD8, Human
caspase recruitment domain family, member 8

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0056873
Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0057978
List Price:    $146.00
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PrimePCR™ SYBR® Green Assay: CARD8, Human
caspase recruitment domain family, member 8

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0013376
List Price:    $146.00
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PrimePCR™ Probe Assay: CARD8, Human
caspase recruitment domain family, member 8

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0057978
List Price:    $214.00
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    Related pathways not available
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