Gene:  BCL2A1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators and is up-regulated by different extracellular signals such as granulocyte-macrophage colony-stimulating factor (GM-CSF) CD40 phorbol ester and inflammatory cytokine TNF and IL-1 which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: BCL2A1, Human
BCL2-related protein A1

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0036589
Info:   Same primer pair as used in probe assay qHsaCEP0039313
List Price:    $142.00
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PrimePCR™ Probe Assay: BCL2A1, Human
BCL2-related protein A1

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0039313
List Price:    $208.00
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