Gene:  BACE2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein a member of the peptidase A1 protein family is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: BACE2, Human
beta-site APP-cleaving enzyme 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012156
Info:   Same primer pair as used in probe assay qHsaCIP0028327
List Price:    $142.00
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PrimePCR™ lncRNA SYBR® Green Assay:BACE2, Human
beta-site APP-cleaving enzyme 2

Assay Type: SYBR® Green
Assay Design: exonic
Application: lncRNA Expression
Unique Assay ID: qhsaLED0134535
Info:   Same primer pair as used in probe assay qhsaLEP0211775
List Price:    $138.00
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PrimePCR™ Probe Assay: BACE2, Human
beta-site APP-cleaving enzyme 2

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028327
List Price:    $208.00
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PrimePCR™ lncRNA® Probe Assay:BACE2, Human
beta-site APP-cleaving enzyme 2

Assay Type: Probe
Assay Design: exonic
Application: lncRNA Expression
Unique Assay ID: qhsaLEP0211775
Info:   Same primer pair as used in SYBR assay qhsaLED0134535
List Price:    $202.00
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    Related pathways not available
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