Gene:  APC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion transcriptional activation and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP) an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: APC, Human
adenomatous polyposis coli

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0012226
Info:   Same primer pair as used in probe assay qHsaCIP0028348
List Price:    $142.00
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PrimePCR™ Probe Assay: APC, Human
adenomatous polyposis coli

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0028348
List Price:    $208.00
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