Gene:  ALDH2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase cytosolic and mitochondrial can be distinguished by their electrophoretic mobilities kinetic properties and subcellular localizations. Most Caucasians have two major isozymes while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform which has a low Km for acetaldehydes and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq Mar 2011]

PrimePCR™ SYBR® Green Assay: ALDH2, Human
aldehyde dehydrogenase 2 family (mitochondrial)

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0043366
Info:   Same primer pair as used in probe assay qHsaCEP0050628
List Price:    $142.00
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PrimePCR™ SYBR® Green Assay: ALDH2, Human
aldehyde dehydrogenase 2 family (mitochondrial)

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0023189
Info:   Recommended - best coverage
List Price:    $142.00
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PrimePCR™ Probe Assay: ALDH2, Human
aldehyde dehydrogenase 2 family (mitochondrial)

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0050628
List Price:    $208.00
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