Gene:  ACVR2B, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins composed of a ligand-binding extracellular domain with cysteine-rich region a transmembrane domain and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ACVR2B, Human
activin A receptor, type IIB

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0016227
Info:   Same primer pair as used in probe assay qHsaCIP0030450
List Price:    $142.00
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PrimePCR™ Probe Assay: ACVR2B, Human
activin A receptor, type IIB

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0030450
List Price:    $208.00
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