Gene:  ABL1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation cell division cell adhesion and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript with alternatively spliced first exons spliced to the common exons 2-11. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ABL1, Human
c-abl oncogene 1, non-receptor tyrosine kinase

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0006676
Info:   Same primer pair as used in probe assay qHsaCIP0026252
List Price:    $146.00
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PrimePCR™ lncRNA SYBR® Green Assay:ABL1, Human
c-abl oncogene 1, non-receptor tyrosine kinase

Assay Type: SYBR® Green
Assay Design: exonic
Application: lncRNA Expression
Unique Assay ID: qhsaLED0104639
Info:   Same primer pair as used in probe assay qhsaLEP0181879
List Price:    $142.00
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PrimePCR™ Probe Assay: ABL1, Human
c-abl oncogene 1, non-receptor tyrosine kinase

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026252
List Price:    $214.00
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PrimePCR™ lncRNA® Probe Assay:ABL1, Human
c-abl oncogene 1, non-receptor tyrosine kinase

Assay Type: Probe
Assay Design: exonic
Application: lncRNA Expression
Unique Assay ID: qhsaLEP0181879
Info:   Same primer pair as used in SYBR assay qhsaLED0104639
List Price:    $208.00
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