Gene:  ABCC2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS) an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: ABCC2, Human
ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Assay Type: SYBR® Green
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCID0008411
Info:   Same primer pair as used in probe assay qHsaCIP0026787
List Price:    $142.00
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PrimePCR™ Probe Assay: ABCC2, Human
ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Assay Type: Probe
Assay Design: Intron-spanning
Application: Gene Expression
Unique Assay ID: qHsaCIP0026787
List Price:    $208.00
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