PrimePCR™ lncRNA® Probe Assay:BACE2, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0134535

List Price:    $202.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0211775
Assay Design:   exonic
Chromosome Location:   chr21:41245962-41246061question
Amplicon Length:   70
Splice Variants Targeted:   ENST00000463674 ENST00000487994 ENST00000465326 ENST00000491838 ENST00000328735 ENST00000330333 ENST00000347667 ENST00000466122
LNCipedia Splice Variants Targeted:   lnc-FAM3B-5:1

Gene Information

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein a member of the peptidase A1 protein family is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   BACE2
Gene Name:   beta-site APP-cleaving enzyme 2
Aliases:   AEPLC, ALP56, ASP1, ASP21, BAE2, CEAP1, DRAP
RefSeq:   NC_000021.8 NT_011512.11
Ensembl:   ENSG00000182240
LNCipedia:   lnc-FAM3B-5
Entrez:   25825
UniGene:   Hs.529408
Chromosome Mapping:   21q22.3
Gene Strand:   Not Available

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