PrimePCR™ lncRNA® Probe Assay:AVP, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0134511

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PrimePCR™ IncRNA PreAmp for Probe Assay: AVP, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: AVP, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0211751
Assay Design:   exonic
Chromosome Location:   chr20:3083165-3084635question
Amplicon Length:   64
Refseq Transcripts Amplified:   XM_011529267,NM_000490
Splice Variants Targeted:   ENST00000380293
LNCipedia Splice Variants Targeted:   lnc-AVP-1:1

Gene Information

This gene encodes a precursor protein consisting of arginine vasopressin and two associated proteins neurophysin 2 and a glycopeptide copeptin. Arginine vasopressin is a posterior pituitary hormone which is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein neurophysin 2 it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition tolerance adaptation and complex sexual and maternal behaviour as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). [provided by RefSeq Mar 2010]

Gene Symbol:   AVP
Gene Name:   arginine vasopressin
Aliases:   ADH, ARVP, AVP-NPII, AVRP, VP
RefSeq:   NC_000020.10 NG_008663.1 NT_011387.8
Ensembl:   ENSG00000101200
LNCipedia:   lnc-AVP-1
Entrez:   551
Chromosome Mapping:   20p13
Gene Strand:   Not Available

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