PrimePCR™ lncRNA® Probe Assay:ABCG5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   Same primer pair as used in SYBR assay qhsaLED0104678

List Price:    $247.00
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PrimePCR™ IncRNA PreAmp for Probe Assay: ABCG5, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ IncRNA Template for Probe Assay: ABCG5, Human
Reaction:     4 billion copies/200 µl
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   lncRNA Expression
Unique Assay ID:   qhsaLEP0181918
Assay Design:   exonic
Chromosome Location:   chr2:43812842-43812955question
Amplicon Length:   84
Refseq Transcripts Amplified:   XM_011533026,XM_011533024,XM_011533025,XM_011533027,XM_011533028,NM_022436
Splice Variants Targeted:   ENST00000486512 ENST00000260645 ENST00000405322 ENST00000409962
LNCipedia Splice Variants Targeted:   lnc-LRPPRC-3:1

Gene Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver colon and intestine. This gene is tandemly arrayed on chromosome 2 in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis and have been observed in patients with sitosterolemia. [provided by RefSeq Jul 2008]

Gene Symbol:   ABCG5
Gene Name:   ATP-binding cassette, sub-family G (WHITE), member 5
Aliases:   STSL
RefSeq:   NC_000002.11 NG_008883.1 NG_008884.1 NT_022184.15
Ensembl:   ENSG00000138075
LNCipedia:   lnc-LRPPRC-3
Entrez:   64240
Chromosome Mapping:   2p21
Gene Strand:   Not Available

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