PrimePCR™ lncRNA SYBR® Green Assay:PABPN1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qhsaLEP0211625

List Price:    $142.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   lncRNA Expression
Unique Assay ID:   qhsaLED0134385
Assay Design:   exonic
Chromosome Location:   chr14:23325998-23326150question
Amplicon Length:   123
Splice Variants Targeted:   ENST00000397276 ENST00000216727
LNCipedia Splice Variants Targeted:   lnc-BCL2L2-PABPN1-1:3 lnc-BCL2L2-PABPN1-1:2

Gene Information

This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq Dec 2010]

Gene Symbol:   PABPN1
Gene Name:   poly(A) binding protein, nuclear 1
Aliases:   OPMD, PAB2, PABII, PABP-2, PABP2
RefSeq:   NC_000014.8 NG_008239.1 NT_026437.12
Ensembl:   ENSG00000100836
LNCipedia:   lnc-BCL2L2-PABPN1-1
Entrez:   8106
UniGene:   Hs.707712
Chromosome Mapping:   14q11.2-q13
Gene Strand:   Not Available

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