PrimePCR™ lncRNA SYBR® Green Assay:CBL, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression.

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qhsaLEP0181622

List Price:    $142.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   lncRNA Expression
Unique Assay ID:   qhsaLED0104382
Assay Design:   exonic
Chromosome Location:   chr11:119299823-119299960question
Amplicon Length:   108
Refseq Transcripts Amplified:   NM_005188,XM_017018511
Splice Variants Targeted:   ENST00000264033 ENST00000634840
LNCipedia Splice Variants Targeted:   lnc-RNF26-1:1

Gene Information

This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq Mar 2012]

Gene Symbol:   CBL
Gene Name:   Cas-Br-M (murine) ecotropic retroviral transforming sequence
Aliases:   C-CBL, CBL2, RNF55
RefSeq:   NC_000011.9 NG_016808.1 NT_033899.8
Ensembl:   ENSG00000110395
LNCipedia:   lnc-RNF26-1
Entrez:   867
UniGene:   Hs.504096
Chromosome Mapping:   11q23.3
Gene Strand:   Not Available

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