This is the amplicon context sequence in accordance with the minimum information for the publication of real-time quantitative PCR experiements (MIQE) guidelines. For more details, please refer to the following publication, "Primer Sequence Disclosure: A Clarification of the MIQE Guidelines."
Real-time PCR primer assay designed for SYBR® Green gene expression analysis.
Info: Same primer pair as used in probe assay qhsaLEP0181329
PrimePCR™ IncRNA PreAmp for SYBR® Green Assay: SP1, Human
PrimePCR™ IncRNA Template for SYBR® Green Assay: SP1, Human
The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes including cell differentiation cell growth apoptosis immune responses response to DNA damage and chromatin remodeling. Post-translational modifications such as phosphorylation acetylation glycosylation and proteolytic processing significantly affect the activity of this protein which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2011]